Sickle Cell Anemia Test with Reflex

Our Sickle Cell Anemia Test with Reflex detects abnormal types of hemoglobin in the blood (hemoglobin-S and hemoglobin-C Harlem). An initial screening of your blood sample is performed, and if abnormalities are found, additional tests are performed to determine which type of abnormal hemoglobin is present. These tests are used by physicians to help diagnose sickle cell anemia, a genetic blood disorder caused by a gene mutation. Sickle cell anemia affects the shape of red blood cells that carry oxygen through the body, causing pain, anemia (low red blood count), and infections.
$49.00
+ $6.00 Physician Service Fee

Who is getting tested? *

Test Type

Do you have any of the following severe symptoms associated with Sickle Cell Anemia?

Please seek immediate care from your primary care physician.

Please seek immediate care from your primary care physician.

Please seek immediate care from your primary care physician.

Please seek immediate care from your primary care physician.

Please seek immediate care from your primary care physician.

Unfortunately this test is not right for you based on your responses.
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What
Our Sickle Cell Anemia Test with Reflex includes a sickle cell screen for the presence of abnormal types of hemoglobin, and if positive, a reflex test to hemoglobinopathy evaluation to determine the presence of sickle hemoglobin proteins (hemoglobin S and Hemoglobin C-Harlem) to help identify people with sickle cell anemia or sickle cell trait.
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Who

Must be 18+ years of age to purchase

Orders not permitted in: AK, HI, AZ

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How
Type of sample to be collected:
• Blood (venipuncture - a needle is used to draw blood from a vein)
Schedule an appointment, and then visit one of our Patient Service Centers
About the Test

The Sickle Cell Anemia Test with Reflex includes a sickle cell screen for Hemoglobin-S and Hemoglobin C Harlem, which are abnormal types of hemoglobin. Hemoglobin is the protein in red blood cells that carries oxygen throughout the body. Red blood cells are usually round and flexible and can move easily through blood vessels. In sickle cell anemia, some of the red blood cells are c-shaped like sickles or crescents and can become rigid and difficult to pass through the bloodstream. This can slow down or block blood flow and decrease oxygen levels. Hemoglobin-S cells have a shorter lifespan than regular hemoglobin cells, which can lead to a severe shortage of healthy red blood cells (anemia).

The sickle cell screen can indicate a positive or negative presence of Hemoglobin-S and/or Hemoglobin-C Harlem. If your sickle cell screen is positive, a hemoglobinopathy evaluation will be conducted at no additional charge to help determine sickle cell disease or trait. The Hemoglobinopathy evaluation will provide results for Hemoglobin A, Hemoglobin A2, and any hemoglobin variants.

Sickle Cell Anemia Test with Reflex

Take an in-person test at a Quest Diagnostics location.
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1. Purchase your test
Schedule your appointment after purchasing a test to minimize wait time.
2. Visit a location
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3. Get results online
We will email you when your confidential results are available. 

The benefits of testing

You can get the information you need to support a healthy life - for yourself.

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Take control of your health

Conveniently shop and pay online for lab tests without a doctor's visit. An independent physician will review your request and if appropriate, confirm your order and offer oversight.

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Schedule and manage your appointments

Conveniently schedule your appointment online at one of our Quest Diagnostics locations. Certain tests may also offer self-testing home delivery.

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Get your results online

View your results through your secure account online. And it's easy to share the result with your doctor.

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