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Progesterone Test

$89.00

+ $6.00 Physician Service Fee

HSA/FSA Accepted

Understand your progesterone level to gain insight into hormone balance, reproductive health, and overall wellness—for men and women. Read more

Quantity

What

The Progesterone Test measures the level of progesterone on day 21 of your cycle to determine if you’re ovulating. It may also help detect fertility problems.

Who

Must be 18+ years of age to purchase.

How

Blood

Where

Find a location near you

Schedule an appointment, then visit a Quest Diagnostics patient service center location.

This blood test measures progesterone, a hormone that plays an important role in reproductive health and overall hormone balance in both women and men. Progesterone imbalance, which typically presents as low levels, may cause symptoms like infertility, weight gain, anxiety, depression, fatigue, sleep disturbances, and low libido in both men and women.

In women, progesterone is a vital hormone that prepares the uterus for pregnancy, regulates the menstrual cycle, and supports early pregnancy. In men, progesterone is a crucial, often overlooked hormone that acts as a precursor to testosterone, balances estrogen levels, and supports sperm production. Progesterone levels naturally vary based on sex, age, and the timing of the menstrual cycle for women.

Measuring your level at a specific point in time can help provide insight into how your body is functioning and whether additional follow-up with an independent healthcare provider may be needed.

No doctor’s visit needed. Buy this progesterone blood test, visit a nearby Quest location, and get fast results.

Sample type: Blood
Test type: In Person
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Preparation: For women, it’s recommended that this test be taken 7 days before the start of your next menstrual period (example: 21 days into a 28-day cycle. Cycle day 1 is the first day of your period). If you are not having menstrual cycles, the test can be performed at your convenience. For men, no special preparation is required.

This test may be right for you if:

Women

You have symptoms that may be related to hormone imbalance
You want to evaluate hormone balance as part of overall health
You’re trying to conceive or evaluate fertility
You have irregular periods or abnormal bleeding
You want to know if you’ve ovulated

For a more expanded view of your hormones, Quest offers the Women's Hormone Test Panel — Expanded, which includes progesterone as well as 9 additional hormones and 1 antibody.

Men

You have symptoms that may be related to hormone imbalance
You want to evaluate hormone balance as part of overall health
You want to insight into fertility

This test measures the level of progesterone in your blood.

For women, progesterone is a hormone that not only supports menstruation but also the early stages of pregnancy. Progesterone is mostly made in the ovaries, but the adrenal glands and placenta (during pregnancy) also produce it. Each month, progesterone prepares your uterus for pregnancy. It’s responsible for thickening the lining of the uterus so that a fertilized egg can attach and grow. If conception occurs, progesterone levels remain high to support the pregnancy. If conception doesn’t occur, progesterone levels drop, and the lining of the uterus sheds during menstruation. Too much progesterone can cause heavy periods, bloating, mood changes, or weight gain. Too little progesterone can cause irregular menstrual cycles, difficulty getting pregnant, and early pregnancy loss. It can also cause side effects similar to menopause, like hot flashes, night sweats, mood changes, or missed periods. This test can indicate if ovulation occurred, but does not predict the most fertile days of your cycle.

For men, progesterone is a precursor to testosterone, helping to maintain healthy levels and aiding in testicular function. It helps counteract high estrogen levels, which can otherwise lead to weight gain and other issues. Adequate levels of progesterone in men are associated with reduced inflammation and lower risks of prostate issues. Progesterone also plays a significant role in sperm maturation and motility, which can impact fertility.

Signs & symptoms of progesterone imbalance in women may include:

Irregular menstrual periods
Headaches
Difficulty conceiving
Mood changes, anxiety or depression
Trouble sleeping
Hot flashes
Bloating or weight gain

Signs & symptoms of progesterone imbalance in men may include:

Depression, mood swings, or anxiety
Low sex drive
Weight gain
Erectile dysfunction
Loss of muscle mass
Fatigue and trouble concentrating
Increased risk of prostate cancer

Purchaser: You must be 18 years of age or older to purchase a test on questhealth.com.

Patient: This test can be performed on patients between 18 and 100 years old.

Sample collection: This test requires sample collection at a Quest Diagnostics location or through Quest Mobile® where available, a convenient option for in-home sample collection*. Collection is not available in AZ, HI, or PR.

*Check your zip code here for service availability, not available in all locations. Quest Mobile is currently only available for individuals ages 18+.

For women, it’s recommended that this test be taken 7 days before the start of your next menstrual period (example: 21 days into a 28-day cycle. Cycle day 1 is the first day of your period). If you are not having menstrual cycles, the test can be performed at your convenience. For men, no special preparation is required.

After you provide your specimen, it generally takes few business days to process and release your test results. However, processing times may vary. Your test results will be available in a clear and easy-to-read report. If you have or create a MyQuest® account, you may be able to review your new results there with your other Quest results. Independent healthcare providers are available to discuss questions or concerns you may have regarding your results.

How it works

questhealth.com offers 150+ consumer-initiated Quest Diagnostics lab tests to empower you to have more control over your health journey. Choose from a variety of test types that best suit your needs.

In-person
In-home sample collection

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No doctor visit is required for purchase, but an independent healthcare provider is involved throughout the process.

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Register your test
& schedule an appointment

Book a visit to one of 2000+ Quest locations.

Visit Quest for sample collection

Complete your test sample collection during your scheduled appointment.

Get fast results

Access results online as soon as they’re available. You will be emailed when they are ready. Discuss your results with an independent healthcare provider at no extra cost. Treatment options may be available.

Buy a lab test
+ in-home sample collection

No doctor visit required for purchase. If in-home service is available in your area, purchase for an additional $79 fee.

Buy now

Register your test
& schedule an appointment

After you make a purchase, register your test and Quest Mobile will contact you to schedule an in-home sample collection appointment.

In-home sample collection

A Quest Mobile phlebotomist will collect your sample and deliver it to Quest Diagnostics.

Get fast results

Please note: Quest Mobile is currently only available for individuals ages 18+.

We’ve put together a guide to provide some answers and support for your journey to parenthood.

Progesterone is a hormone that not only supports menstruation but also the early stages of pregnancy. Read our article to learn more about essential hormones and the role they play in reproductive health.

FAQs

How do progesterone levels correlate with pregnancy?

Progesterone is a reproductive hormone that supports pregnancy by preparing the uterine lining to support implantation. Levels are low during a woman’s cycle until they are temporarily elevated as the egg is released during ovulation and for 7-14 days after. If fertilization of the egg occurs, progesterone levels continually rise until birth. If pregnancy does not occur, progesterone levels return to their normal low level by the start of your next period.

Is a progesterone test the same thing as a PdG test like Proov Confirm?

This Progesterone Test is a blood test that detects the level of progesterone. PdG (pregnanediol glucuronide) is a marker of the hormone progesterone. A PdG test detects metabolized progesterone in the first morning urine which is also elevated after ovulation. A PdG test is an additional way to test that ovulation has occurred.

What is progesterone?

Progesterone is a hormone involved in reproductive health and hormone balance. In women, it helps regulate the menstrual cycle and supports pregnancy. In men, it plays a role in hormone production.

Is this test for both men and women?

Yes. While progesterone is often associated with women’s health, it is also present in men and contributes to overall hormone balance.

When is the best time to take this test?

Women: Typically about 7 days before your expected period*
Men: Can be tested at any time

*Timing of the test matters for women because progesterone levels rise after ovulation and fall before menstruation. Testing at the right time in your cycle helps provide more meaningful results.

Can this test diagnose a medical condition?

No. This test measures the level of your progesterone in your blood but is not used alone to diagnose conditions. Results should be reviewed with a healthcare provider.

Can I use my FSA or HSA funds to purchase tests at questhealth.com?

You may be able to use your FSA or HSA funds to purchase lab tests at questhealth.com. Please review your FSA/HSA plan or check with a tax professional to confirm specific requirements for individual eligibility.

Are tests purchased from questhealth.com covered by my health insurance?

Tests purchased on questhealth.com are intended for individuals paying directly—we do not bill insurance, and purchases cannot be submitted for insurance reimbursement.

If your doctor ordered a lab test for you and you are looking to book an appointment for sample collection, you can schedule an appointment here https://appointment.questdiagnostics.com/as-home.

For other questions related to a lab test your doctor ordered for you, including billing and results, you can visit the main Quest Diagnostics site here https://www.questdiagnostics.com.

Our references

MedlinePlus. Progesterone Test. Accessed April 24, 2026. https://medlineplus.gov/lab-tests/progesterone-test/
Cleveland Clinic. Progesterone: Function and Levels. Accessed April 23, 2026. https://my.clevelandclinic.org/health/body/24562-progesterone
Testing.com (AACC). Progesterone Test. Accessed April 23, 2026. https://www.testing.com/tests/progesterone/
Endocrine Society. Hormone Health Resources. Accessed April 24, 2026. https://www.endocrine.org/patient-engagement/endocrine-library/hormones-and-endocrine-function
Cleveland Clinic. Low Progesterone. Accessed May 4, 2026. https://my.clevelandclinic.org/health/diseases/24613-low-progesterone

Tests purchased on questhealth.com are only for individuals who intend to pay directly for testing and do not want to submit a claim for reimbursement under their health insurance.

Progesterone Test