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Lyme Disease Test With Confirmation
Lyme Disease Test With Confirmation
Test for Lyme disease using CDC-recommended two-step process. Consider this test if you have been bitten or have symptoms like a "bullseye" rash or fatigue. Read moreTest details
Sample type:
Blood
Preparation:
You do not need to do anything special to prepare for the sample collection.
Fasting is not required for this test.
$89.00
+ $6.00 Physician Service Fee
What
Measures the levels of IgM and IgG antibodies in response to the bacteria Borrelia burgdorferi, which causes Lyme disease.
Who
Must be 18+ years of age to purchase.
How
Blood
Schedule an appointment, then visit a Quest Diagnostics patient service center location.
About the Test
Lyme disease is a bacterial infection spread through the bite of blacklegged ticks, which are commonly called deer ticks. Ticks usually acquire Borrelia burgdorferi bacteria by biting infected animals, such as deer and small rodents. For Lyme disease to be transmitted, an infected tick needs to be attached to the host for 36 to 48 hours.
Our test follows CDC recommended 2-step testing process for Lyme disease. Both steps use the same blood sample for testing. Your sample measures the levels of IgM and IgG antibodies produced in the blood in response to Borrelia burgdorferi bacteria that cause Lyme disease. If your initial test results are positive, a second test is done to confirm results.
How Does it Work?
Take an in-person test at a Quest Diagnostics location.
Over 2000+ locations focus on your safety, confidentiality and convenience.
1. Purchase your test
Schedule your appointment after purchasing a test to minimize wait time.
2. Visit a location
Enter your zip code to find a Quest Diagnostics location closest to you.
3. Get results online
We will email you when your confidential results are available.
Take an in-person test at a Quest Diagnostics location.
Over 2000+ locations focus on your safety, confidentiality and convenience.
1. Purchase your test
Schedule your appointment after purchasing a test to minimize wait time.
2. Visit a location
Enter your zip code to find a Quest Diagnostics location closest to you.
3. Get results online
We will email you when your confidential results are available.
What to expect with Quest

Health insights, on your terms
Get lab work without having to wait and pay for an appointment with a doctor. Shop questhealth.com and choose from 75+ tests – the same quality tests that doctors use and trust, but no doctor visit required for purchase.

Easy to buy & simple to schedule
After your purchase, schedule an appointment at a nearby Quest Diagnostics location and have your specimen sample collected by a trained healthcare professional.

Fast online results, with support
Access test results from your phone as soon as they’re available, with the option to discuss your results with an independent physician at no extra cost.
FAQs
The blacklegged tick spreads the disease in the Northeast, mid-Atlantic, and North Central United States, while the western blacklegged tick spreads the disease on the Pacific Coast.
Several tick types do not appear to transmit Lyme disease, including lone star ticks, the American dog tick, the Rocky Mountain wood tick, and the brown dog tick.
Humans are usually infected through bites from immature ticks known as nymphs, which are extremely small and difficult to see. Nymphs feed in the spring and summer when people are more likely to spend time outdoors. Adult ticks, which are more active during cooler months, can also transmit Lyme disease bacteria, but since they are larger, they are more likely to be discovered and removed before the bacteria can be transmitted.
Lyme disease is a year-round problem, but April through November is considered tick season. Although Lyme disease does not occur nationwide, it may be diagnosed anywhere. In these cases, people often travel between states, and where they live may be different from where they were infected.
In the United States, most infections occur in the following geographical areas1:
- Connecticut
- Delaware
- Maine
- Maryland
- Massachusetts
- Minnesota
- New Hampshire
- New Jersey
- New York
- Pennsylvania
- Rhode Island
- Vermont
- Virginia
- Washington, DC
- West Virginia
- Wisconsin
Ticks cannot fly or jump and can be found on the tips of grasses and shrubs in a variety of outdoor settings, including gardens, lawns, and wooded areas, particularly near trails. Blacklegged ticks are prevalent in wooded, brushy areas where rodents, deer, and other mammals can find food and shelter.
You may be at greater risk for Lyme disease if you live in an area where the disease is more prevalent. Tick bites are most common among campers, hikers, and people who work in gardens and other leafy outdoor environments.
The best defense against Lyme disease is to reduce tick exposure, including taking steps such as the following:
- Treat clothing, boots, camping, and hiking gear with products containing 0.5% permethrin, a pesticide
- Examine your clothing and equipment for ticks
- Check your whole body for ticks daily, including your belly button, hair, ears, and any places that may be difficult to see
- Check pets daily for ticks
- Be alert for fever or rash
- After being outdoors, take a shower as soon as possible
- Remove ticks promptly and correctly
Our references
References
1Centers for Disease Control and Prevention, National Center for Emerging and Zoonotic Infectious Diseases (NCEZID), Division of Vector-Borne Diseases (DVBD). Last reviewed April 29, 2022. www.cdc.gov/lyme/datasurveillance/maps-recent.html
Learn more
Centers for Disease Control and Prevention, National Center for Emerging and Zoonotic Infectious Diseases (NCEZID), Division of Vector-Borne Diseases (DVBD). Last reviewed May 13, 2022. How to remove a tick. https://www.cdc.gov/ticks/removing_a_tick.html