Lyme Disease Test With Confirmation
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Our Lyme Disease Test measures the levels of IgM and IgG antibodies in response to the bacteria Borrelia burgdorferi, which causes Lyme disease.
Treatment options may be available. See more in "After the Test."
Must be 18+ years of age to purchase
Orders not permitted in: AK, HI, AZ
Type of sample to be collected:
Blood (venipuncture - a needle is used to draw blood from a vein)
This test features confirmation testing; see ‘Confirmation’ section for details.

The benefits of testing
You can get the information you need to support a healthy life - for yourself.

Take control of your health
Conveniently shop and pay online for lab tests without a doctor's visit. An independent physician will review your request and if appropriate, confirm your order and offer oversight.

Schedule and manage your appointments
Conveniently schedule your appointment online at one of our Quest Diagnostics locations. Certain tests may also offer self-testing home delivery.

Get your results online
View your results through your secure account online. And it's easy to share the result with your doctor.
The blacklegged tick spreads the disease in the Northeast, mid-Atlantic, and North Central United States, while the western blacklegged tick spreads the disease on the Pacific Coast.
Several tick types do not appear to transmit Lyme disease, including lone star ticks, the American dog tick, the Rocky Mountain wood tick, and the brown dog tick.
Humans are usually infected through bites from immature ticks known as nymphs, which are extremely small and difficult to see. Nymphs feed in the spring and summer when people are more likely to spend time outdoors. Adult ticks, which are more active during cooler months, can also transmit Lyme disease bacteria, but since they are larger, they are more likely to be discovered and removed before the bacteria can be transmitted.
Lyme disease is a year-round problem, but April through November is considered tick season. Although Lyme disease does not occur nationwide, it may be diagnosed anywhere. In these cases, people often travel between states, and where they live may be different from where they were infected.
In the United States, most infections occur in the following geographical areas1:
- Connecticut
- Delaware
- Maine
- Maryland
- Massachusetts
- Minnesota
- New Hampshire
- New Jersey
- New York
- Pennsylvania
- Rhode Island
- Vermont
- Virginia
- Washington, DC
- West Virginia
- Wisconsin
Ticks cannot fly or jump and can be found on the tips of grasses and shrubs in a variety of outdoor settings, including gardens, lawns, and wooded areas, particularly near trails. Blacklegged ticks are prevalent in wooded, brushy areas where rodents, deer, and other mammals can find food and shelter.
You may be at greater risk for Lyme disease if you live in an area where the disease is more prevalent. Tick bites are most common among campers, hikers, and people who work in gardens and other leafy outdoor environments.
The best defense against Lyme disease is to reduce tick exposure, including taking steps such as the following:
- Treat clothing, boots, camping, and hiking gear with products containing 0.5% permethrin, a pesticide
- Examine your clothing and equipment for ticks
- Check your whole body for ticks daily, including your belly button, hair, ears, and any places that may be difficult to see
- Check pets daily for ticks
- Be alert for fever or rash
- After being outdoors, take a shower as soon as possible
- Remove ticks promptly and correctly
References
1Centers for Disease Control and Prevention, National Center for Emerging and Zoonotic Infectious Diseases (NCEZID), Division of Vector-Borne Diseases (DVBD). Last reviewed April 29, 2022. www.cdc.gov/lyme/datasurveillance/maps-recent.html
Learn more
Centers for Disease Control and Prevention, National Center for Emerging and Zoonotic Infectious Diseases (NCEZID), Division of Vector-Borne Diseases (DVBD). Last reviewed May 13, 2022. How to remove a tick. https://www.cdc.gov/ticks/removing_a_tick.html