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Prostate Screening (PSA)
Prostate Screening (PSA)
Measure the level of PSA in your blood, which can increase due to prostate cancer or other noncancerous prostate conditions. Read moreTest details
Sample type:
Blood
Preparation:
You do not have to fast for this test.
You should not ejaculate or exercise vigorously for 48 hours before sample collection since this might affect your test results.
$69.00
+ $6.00 Physician Service Fee
What
PSA is a protein produced in the prostate. Its major function is to liquify semen. This test measures the level of prostate-specific antigen in the blood.
Who
Must be 18+ years of age to purchase.
How
Blood
Schedule an appointment, then visit a Quest Diagnostics patient service center location.
About the Test
Measures the level of prostate-specific antigen, or PSA, in your blood which may be elevated due to prostate cancer. However, high levels of PSA do not always indicate the presence of prostate cancer. Other prostate conditions such as enlarged prostate (benign prostatic hyperplasia) or inflammation of the prostate (prostatitis) can also increase PSA levels. PSA levels also increase with age. If PSA levels are elevated, it's important to discuss your results with a healthcare provider.
How Does it Work?
Take an in-person test at a Quest Diagnostics location.
Over 2000+ locations focus on your safety, confidentiality and convenience.
1. Purchase your test
Schedule your appointment after purchasing a test to minimize wait time.
2. Visit a location
Enter your zip code to find a Quest Diagnostics location closest to you.
3. Get results online
We will email you when your confidential results are available.
Take an in-person test at a Quest Diagnostics location.
Over 2000+ locations focus on your safety, confidentiality and convenience.
1. Purchase your test
Schedule your appointment after purchasing a test to minimize wait time.
2. Visit a location
Enter your zip code to find a Quest Diagnostics location closest to you.
3. Get results online
We will email you when your confidential results are available.
What to expect with Quest

Health insights, on your terms
Get lab work without having to wait and pay for an appointment with a doctor. Shop questhealth.com and choose from 75+ tests – the same quality tests that doctors use and trust, but no doctor visit required for purchase.

Easy to buy & simple to schedule
After your purchase, schedule an appointment at a nearby Quest Diagnostics location and have your specimen sample collected by a trained healthcare professional.

Fast online results, with support
Access test results from your phone as soon as they’re available, with the option to discuss your results with an independent physician at no extra cost.
FAQs
There are several reasons why PSA levels may be higher than normal:
- Age: As men get older, their PSA levels tend to rise
- Benign prostatic hyperplasia (BPH): In some men, the prostate grows bigger and produces more PSA than usual due to its larger size
- Medications: Some medications, such as finasteride and some cholesterol-lowering medications, can alter your PSA level. Be sure to tell your provider about any medications you are taking before your PSA test
- Prostate cancer: In a healthy prostate, PSA is secreted in small amounts into the bloodstream, but levels can increase as cancer develops
- Prostatitis: Prostatitis is a painful condition in which the prostate is inflamed, swollen, and tender. It is often caused by a bacterial infection, though sometimes the cause is unknown. In some cases, PSA level may increase because of irritation of the prostate
- Urinary tract infection: An infection in the urinary system can irritate the prostate and cause inflammation. This can cause the prostate to make more PSA
Men, especially those between 55 and 69 years old, who want to monitor their prostate health or are at risk for prostate conditions may consider a PSA Test. If you are over 40 years old and have certain risk factors, you may also consider this test after consulting with a healthcare provider to determine if you could benefit from the test.
The American Cancer Society (ASC) encourages men to have a discussion with a healthcare provider about whether prostate cancer screening is appropriate for them.1 For those who choose to have prostate cancer screening, the ACS recommends the PSA blood test for individuals in the following risk categories:
- Men 50 years of age with an average risk of developing prostate cancer and no underlying health conditions that may reduce life expectancy
- Men 45 years of age with a high risk of developing prostate cancer, including African American men and those with an immediate family member who was diagnosed with prostate cancer before the age of 65
- Men 40 years of age with a higher risk of developing prostate cancer, such as individuals with multiple immediate family members with prostate cancer who were diagnosed at an early age
Prostate cancer screening is not recommended for men who do not meet these criteria. Speak with your primary care provider to better understand your own risk.
Our references
1Who Is at Risk for Prostate Cancer? Centers for Disease Control and Prevention. August 25, 2022.
www.cdc.gov/cancer/prostate/basic_info/risk_factors.htm
2American Cancer Society Recommendations for Prostate Cancer Early Detection. April 23, 2021.
www.cancer.org/cancer/prostate-cancer/detection-diagnosis-staging/acs-recommendations.html
*Prostate Cancer.
*https://www.cdc.gov/cancer/prostate/