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Coenzyme Q10 (CoQ10) Test
$69.00
+ $6.00 Physician Service Fee
HSA/FSA Accepted
Measure your coenzyme Q10 (CoQ10) level with this blood test. CoQ10 is an antioxidant and vitamin-like nutrient that your body relies on to make energy and to protect its cells. Your body keeps the most CoQ10 in the organs that work hardest, like the heart, liver, and muscles, and your natural supply slowly drops as you get older. This test can be a helpful check if you take a CoQ10 supplement, if you take a statin, or if you just want to monitor your heart and energy health.
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How
Blood
FAQs
Coenzyme Q10 (CoQ10) is a vitamin-like compound your body both obtains from food and makes on its own. It helps your cells produce energy and works as an antioxidant that helps protect them. You have CoQ10 in nearly all of your tissues, with the most amounts in high-energy muscles and organs like the heart and liver.
Antioxidants are substances that can prevent or slow damage to cells caused by oxidative stress. They interact with toxins called free radicals, to minimize their damage. Antioxidants can help counter oxidative stress, which can play a role in conditions such as cancer, heart disease, and more.5
In your results, you will see a reference range that represents the distribution of normal results, so you can see where you fall. Age, diet, supplements, and cholesterol levels can all move the number, so your healthcare provider can help you make sense of a normal CoQ10 level in the context of your health. Generally, a high level is not considered problematic as CoQ10 does not tend to accumulate in body tissues like other vitamins, such as A or D, but low levels can lead to some of the general symptoms listed in the Signs and symptoms section above.
CoQ10 levels naturally decline with age. Diet plays a part, since some of your CoQ10 comes from food. Certain medications and health conditions are also linked to lower levels. A single result is best understood in the bigger picture of your health, so your healthcare provider can help you interpret it, as this test can only measure the level in your blood, and does not measure how well your body absorbs and uses CoQ10. Low CoQ10 symptoms, when they occur, are usually general, such as tiredness or muscle aches.
A higher level most often reflects taking a CoQ10 supplement, and it is not usually a health concern. Your healthcare provider can help you understand your results in the context of your supplement use and overall health.
If you take a CoQ10 supplement, this test can help you see whether your blood level is where you would expect it to be. For the most useful result, consider not taking your CoQ10 supplement on the morning of the test. If you are concerned about any of your supplements or medications impacting your results, talk to your healthcare provider before your sample is collected to see if you should stop taking them and for how long.
They are closely related: ubiquinone is the oxidized form of CoQ10; ubiquinol is the reduced, active form; and ubisemiquinone is the half-reduced form. Your body switches back and forth between the three as CoQ10 does its work, and generally about 90-95% of CoQ10 exists in the reduced form in healthy individuals.6 This test measures your total CoQ10 and does not report any amounts separately.
Statins work to lower cholesterol but may interfere with the process that the body uses to make CoQ10. Researchers have spent years looking at whether statins lower your CoQ10 levels. So far, the findings are mixed, with the strongest evidence showing that supplementation may help relieve migraines, restore levels that have reduced due to age or statin use, and aid in supporting those experiencing heart failure.4
This test can show your current CoQ10 status, but it cannot tell you whether a statin is causing any symptoms you may have. Talk to your healthcare provider about any muscle symptoms or medication questions, and do not stop any prescribed medications without medical guidance.
Your body makes some CoQ10 on its own, and the rest comes from what you eat. Foods high in CoQ10 include oily fish (such as salmon and sardines), and organ meats, while smaller amounts are found in nuts, seeds, and some vegetables. The CoQ10 found in food comprises only one part of your overall level, though, since your body produces much of its own.
Water-soluble and fat-soluble vitamins differ in how they are absorbed by the human body. A water-soluble vitamin dissolves in water and is easily absorbed by the body. Your body does not store these vitamins for long, so any extra will be eliminated in your urine. Because of this, it's important to consume them every day.
A fat-soluble vitamin dissolves in fats and oils and is absorbed with the fats you eat. Your body stores any extra in your liver or fatty tissues. Because of this, you don't need to consume them every day.
No. This test measures the total CoQ10 in your blood and is not used to diagnose inherited (primary) CoQ10 deficiency, which needs specialized testing (sometimes including a muscle sample). If a serious deficiency is suspected, your healthcare provider can guide the right testing.
You may be able to use your FSA or HSA funds to purchase lab tests at questhealth.com. Please review your FSA/HSA plan or check with a tax professional to confirm specific requirements for individual eligibility.
Tests purchased on questhealth.com are intended for individuals paying directly—we do not bill insurance, and purchases cannot be submitted for insurance reimbursement.
If your doctor ordered a lab test for you and you are looking to book an appointment for sample collection, you can schedule an appointment here https://appointment.questdiagnostics.com/as-home.
For other questions related to a lab test your doctor ordered for you, including billing and results, you can visit the main Quest Diagnostics site here https://www.questdiagnostics.com.
Our references
- British Journal of Cardiology. Coenzyme Q10 and cardiovascular disease: an overview. Accessed August 31, 2026. https://bjcardio.co.uk/2015/10/coenzyme-q10-and-cardiovascular-disease-an-overview/
- Qu, Hua et al. “The effect of statin treatment on circulating coenzyme Q10 concentrations: an updated meta-analysis of randomized controlled trials.” European journal of medical research vol. 23,1 57. 10 Nov. 2018, doi:10.1186/s40001-018-0353-6 https://pubmed.ncbi.nlm.nih.gov/30414615/
- Banach, Maciej et al. “Statin therapy and plasma coenzyme Q10 concentrations--A systematic review and meta-analysis of placebo-controlled trials.” Pharmacological research vol. 99 (2015): 329-36. doi:10.1016/j.phrs.2015.07.008 https://pubmed.ncbi.nlm.nih.gov/26192349/
- Mayo Clinic. Coenzyme Q10. Accessed August 2026. https://www.mayoclinic.org/drugs-supplements-coenzyme-q10/art-20362602
- Cleveland Clinic. Oxidative Stress. Accessed August 31, 2026. https://my.clevelandclinic.org/health/articles/oxidative-stress
- Aaseth, Jan, et al. Coenzyme Q10 supplementation – In ageing and disease. Mechanisms of Ageing and Development, Volume 197, 2021, 111521, ISSN 0047-6374. https://doi.org/10.1016/j.mad.2021.111521
- Cleveland Clinic. Can a CoQ10 Supplement Help If I'm Taking a Statin? Accessed August 2026. https://health.clevelandclinic.org/can-coq10-supplement-help-im-taking-statin
- MedlinePlus. Coenzyme Q10. Accessed August 2026. https://medlineplus.gov/genetics/condition/primary-coenzyme-q10-deficiency/
- Quest Diagnostics. Coenzyme Q10, Test Code 19826. Accessed August 2026. https://testdirectory.questdiagnostics.com/test/test-detail/19826/coenzyme-q10
- Journal of the American Heart Association. Effects of Coenzyme Q10 on Statin-Induced Myopathy: An Updated Meta-Analysis. Accessed August 2026. https://www.ahajournals.org/doi/full/10.1161/JAHA.118.00983
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