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Tuberculosis Blood Test
Tuberculosis Blood Test
Detect tuberculosis bacteria in the body. This test is for those who have been exposed to tuberculosis bacteria (Mycobacterium tuberculosis); require evidence of a negative tuberculosis test; or are at high risk for contracting tuberculosis. Read moreTest details
Sample type:
Blood
Preparation:
You do not need to do anything special to prepare for the sample collection.
Fasting is not required for this test.
$149.00
+ $6.00 Physician Service Fee
What
Detect Mycobacterium tuberculosis, the bacteria that causes Tuberculosis (TB). This is detected in both active TB and latent TB.
Who
Must be 18+ years of age to purchase.
How
Blood
Schedule an appointment, then visit one of the Quest Diagnostics Patient Service Centers
About the Test
This test is an Interferon-Gamma Release Assays (IGRAs) whole-blood test that detects the immune system’s response to M. tuberculosis. M. tuberculosis, or TB bacteria, usually attack the lungs. However, TB bacteria can attack any part of the body such as the spine, kidneys, and brain. In fact, not everyone that becomes infected with TB bacteria will become sick. As a result, two TB-related conditions exist: latent TB infection (LTBI) and TB disease. If not treated properly, TB disease can be fatal. This test does not differentiate between latent tuberculosis infection (LTBI) and active TB disease.
LTBI is a carrier state of TB that can last for weeks, months, or years before developing into TB disease. Active TB is when tuberculosis bacteria overwhelm a person's immune system, and symptoms start to appear. The Tuberculosis Blood Test helps detect the presence of M. tuberculosis and can be a first step in the process of determining is someone has latent TB infection or TB disease. Further testing may be required if the blood test is positive.
What to expect with Quest

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Easy to buy & simple to schedule
After your purchase, schedule an appointment at a nearby Quest Diagnostics location and have your specimen sample collected by a trained healthcare professional.

Fast online results, with support
Access test results from your phone as soon as they’re available, with the option to discuss your results with an independent physician at no extra cost.
FAQs
- The results are either positive or negative, and have a lower risk of reader bias when compared to a skin test
- Accuracy is not affected by a prior bacillus Calmette-Guérin (BCG) TB vaccination
- Only requires a single patient visit (2 to 4 are required for the TST)
No, a prior TST does not boost, or provide a false positive for IGRA results, however a previous infection may.
Live-virus vaccines may affect IGRA test results. However, the effect of live-virus vaccination on IGRAs has not been studied. Until more information is available, the CDC recommends that IGRA testing for live-virus vaccinations are performed as follows:
- Either on the same day as a live-virus vaccination or 4 to 6 weeks after the administration of a live-virus vaccination
- At least 1 month after a smallpox vaccination
You should not delay a COVID-19 vaccination due to testing for TB. The COVID-19 vaccine is not a live-virus vaccine. It does not affect the results of the TB blood test.
Our references
*Data and Statistics. https://www.cdc.gov/tb/statistics/default.htm
**Tuberculosis (TB) https://www.cdc.gov/tb/