Deep dive into your thyroid health
Your thyroid is a small gland with a big job. It produces hormones that help regulate your metabolism, energy levels, body temperature, heart rate, digestion, and many other important functions.
Because thyroid symptoms often develop gradually and can overlap with other health conditions, it isn't always easy to know if your thyroid may be contributing to the way you feel. Lab testing (for both men and women) can provide valuable information about your thyroid function and help you have a more informed conversation with your healthcare provider.
Not sure where to start? The Comprehensive Thyroid Test Panel measures 3 thyroid hormones and 2 antibodies for a more complete picture of thyroid health.
Symptom checker
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Could it be your thyroid?
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Fatigue or low energy
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Unexplained weight gain or loss
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Changes in mood or concentration
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Sensitivity to temperature
Please note: Thyroid imbalance symptoms can vary and overlap with other conditions. Testing can help give you and your healthcare provider detailed insights into your symptoms.
Common thyroid test markers
Thyroid testing measures different hormones and antibodies to provide a more complete picture of how your thyroid is functioning and whether your immune system may be affecting it.
- TSH (thyroid-stimulating hormone): TSH signals your thyroid to produce thyroid hormones—primarily T4. Often the first test used to evaluate thyroid function
- Free T4 (free thyroxine): The primary hormone made by the thyroid, it converts into the active T3 hormone primarily in the liver and kidneys. It regulates your metabolism (how your body uses energy), heart rate, body temperature, and brain development
- Free T3 (free triiodothyronine): The active thyroid hormone that directly drives your metabolism, energy production, and cognitive function
- TPO antibodies (thyroid peroxidase antibodies): Detects antibodies directed against thyroid peroxidase to see if your immune system is attacking your thyroid. Elevated levels may indicate an autoimmune response affecting the thyroid
- Tg (thyroglobulin antibodies): Detects antibodies against thyroglobulin, a protein made by the thyroid gland that helps produce thyroid hormones. May provide additional information about autoimmune activity involving the thyroid
Learn more about Quest's thyroid tests:
| Comprehensive Thyroid Test Panel | Measures 3 hormones (thyroid-stimulating hormone [TSH], free T3, & free T4) and 2 antibodies (thyroid peroxidase antibodies [TPO] & thyroglobulin antibodies [Tg]) |
| Thyroid Disorder Monitoring — Initial | Measures thyroid-stimulating hormone (TSH), free T4, and thyroid peroxidase antibodies (TPO) |
| Thyroid Disorder Monitoring — Ongoing | Measures the level of thyroid-stimulating hormone (TSH) and free T4 |
| Thyroid TSH Function Test | Measures the level of thyroid-stimulating hormone (TSH) to help determine if your thyroid gland is functioning properly |
| Thyroid Disorder Nutrient Deficiency Panel | Measures the levels of the following 5 nutrients in your blood: vitamin D, iodine, ferritin, iron, and selenium |
The thyroid & autoimmune connection
Some thyroid conditions are caused by the immune system mistakenly attacking the thyroid gland. These are known as autoimmune thyroid diseases. Testing for thyroid antibodies can provide additional information when thyroid disease is suspected, particularly if thyroid hormone levels are abnormal or symptoms continue despite normal routine thyroid testing.
Thyroid Peroxidase (TPO) Antibodies
A thyroid peroxidase (TPO) antibody test measures antibodies directed against thyroid peroxidase, an enzyme involved in making thyroid hormones. Elevated TPO antibodies are commonly associated with Hashimoto's thyroiditis, the most common cause of underactive thyroid (hypothyroidism).
Graves' disease is another autoimmune thyroid condition. Unlike Hashimoto's thyroiditis, Graves' disease most often causes the thyroid to become overactive (hyperthyroidism).
Expand your health insights
Skip the hassle of multiple appointments. Now with select Quest Hormone Test Panels you have the flexibility to add on a thyroid test. Whether you’re looking to dive deeper into thyroid function or thyroid antibodies, you can build a more complete picture of your thyroid.
With the ability to bundle additional thyroid tests at checkout, you can get everything done in a single visit to Quest and then receive secure online results.
Are you at risk for nutrient deficiencies?
Thyroid disorders, such as hypothyroidism and Hashimoto’s, may make it difficult for your body to get the nutrients it needs. Measure the levels of 5 nutrients in your blood that research has shown can be affected by thyroid disorders. The Thyroid Disorder Nutrient Deficiency Panel measures the levels of the following 5 nutrients in your blood: vitamin D, iodine, ferritin, iron, and selenium. Shop more nutrient tests below.
Lab work, with less work
Quest makes getting a more complete picture of your hormone health as easy as it should be.
• No doctor visit* or health insurance required for purchase
• No surprise medical bills in the mail
• Buy online and visit a nearby Quest location for sample collection
• Receive fast, online results
• You have the ability to discuss your results with an independent healthcare provider
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*No doctor visit is required to buy your own lab test at questhealth.com. A $6 Physician Service Fee is collected on behalf of PWNHealth and its affiliates for independent physician oversight of lab testing including ordering testing if appropriate. PWNHealth also reviews your test results and will contact you directly if they require prompt attention. Included in each purchase is the ability to discuss your test results with an independent healthcare provider; however, you are also encouraged to speak with your primary healthcare provider.
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